Principal Proposed Uses
What Is Rhubarb Used for Today?
1 Usui T, Ikeda Y, Tagami T, et al. The phytochemical lindleyin, isolated from Rhei rhizoma, mediates hormonal effects through estrogen receptors. J Endocrinol. 2002;175:289-96.
2 Heger M, Ventskovskiy BM, Borzenko I, et al. Efficacy and safety of a special extract of Rheum rhaponticum (ERr 731) in perimenopausal women with climacteric complaints: a 12-week randomized, double-blind, placebo-controlled trial. Menopause . 2006 Aug 4 [Epub ahead of print]
3 Saller R, Buechi S, Meyrat R, et al. Combined herbal preparation for topical treatment of Herpes labialis. Forsch Komplementarmed Klass Naturheilkd. 2002;8:373-382.
4 Choi SZ, Lee SO, Jang KU, et al. Antidiabetic stilbene and anthraquinone derivatives from Rheum undulatum. Arch Pharm Res . 2005;28:1027-1030.
5 Li X, Wang H. Chinese herbal medicine in the treatment of chronic kidney disease. Adv Chronic Kidney Dis. 2005;12:276-281.
6 Fan JG. Evaluating the efficacy and safety of Danning Pian in the short-term treatment of patients with non-alcoholic fatty liver disease: a multicenter clinical trial. Hepatobiliary Pancreat Dis Int . 2004;3:375-380.
7 Jin H, Sakaida I, Tsuchiya M, et al. Herbal medicine Rhei rhizome prevents liver fibrosis in rat liver cirrhosis induced by a choline-deficient L-amino acid-defined diet. Life Sci. 2005;76:2805-2816.
8 Matsuda H, Tewtrakul S, Morikawa T, et al. Anti-allergic activity of stilbenes from Korean rhubarb (Rheum undulatum L.): structure requirements for inhibition of antigen-induced degranulation and their effects on the release of TNF-alpha and IL-4. Bioorg Med Chem. 2004;12:4871-4876.
9 Zhao YQ, Liu XH, Ito T, et al. Protective effects of rhubarb on experimental severe acute pancreatitis. World J Gastroenterol . 2004;10:1005-1009.
10 Finch AM, Kasidas GP, Rose GA. Urine composition in normal subjects after oral ingestion of oxalate-rich foods. Clin Sci (Lond) . 1981;60:411-418.
11 Vahlensieck EW, Bach D, Hesse A, et al. Epidemiology, Pathogenesis and diagnosis of calcium oxalate urolithiasis. Int Urol Nephrol. 1983;14:333-47.
12 Massey LK, Roman-Smith H, Sutton RA. Effect of dietary oxalate and calcium on urinary oxalate and risk of formation of calcium oxalate kidney stones. J Am Diet Assoc . 1993;93:901-906.
13 Hesse A, Siener R, Heynck H, et al. The influence of dietary factors on the risk of urinary stone formation. Scanning Microsc. 1994;7:1119-27; discussion 1127-1128.
14 Goel V, Ooraikul B, Basu TK. Effect of dietary rhubarb stalk fiber on the bioavailability of calcium in rats. Int J Food Sci Nutr . 1997;47:159-163.
15 Mantani N, Sekiya N, Sakai S, et al. Rhubarb use in patients treated with Kampo medicines--a risk for gastric cancer? Yakugaku Zasshi. 2002;122:403-405.
16 Yu HM, Liu YF, Cheng YF, et al. Effects of rhubarb extract on radiation induced lung toxicity via decreasing transforming growth factor-beta-1 and interleukin-6 in lung cancer patients treated with radiotherapy. Lung Cancer. 2007 Sep 14. [Epub ahead of print]
- Reviewer: EBSCO CAM Review Board
- Review Date: 08/2013 -
- Update Date: 08/22/2013 -